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The Trans-Fat Dilemma : Health VS Functionalities
by Kalyana Sundram & Yusof Basiron

Malaysian Palm Oil Council (MPOC), 2nd Floor Wisma Sawit, Lot 6, SS6 Jalan Perbandaran, 47301 Kelana Jaya, Selangor, Malaysia
E-mail: kalyana@mpoc.org.my, yusof@mpoc.org.my

Do Fat Reformulation Efforts Serve Both Functionality and Health?

As indicated earlier, reformulated TFA fats must be proven to be healthier (primarily less cholesterol-raising) than the TFA-rich fats they are designed to replace. Such replacement would preferentially entail the use of natural fats, which are also rich in SFA. The answer may lie in the American Heart Association’s (AHA) Step-1 diet which advocates equal balancing of SFA, MUFA and PUFA in a 30% fat energy diet. This primarily pursues the goal of reducing overall fat consumption, which in turn is postulated to trigger reductions in plasma lipid-lipoprotein associated CHD risk factors. None of the current commercial oils and fats on their own are able to meet this specified fatty acid distribution. Sundram et al. [13]designed an AHA oil blend incorporating soyabean, Canola and palm oils which resulted in a 1:1:1 ratio of the SFA, MUFA and PUFA while being TFA-free. This was tested in healthy normocholesterolaemic volunteers who were fed carefully designed whole food diets and compared against Canola oil (18:1-rich), palm olein (16:0-rich) or the AHA Step-1 diet, all contributing approximately 31% fat energy and < 200mgdietary cholesterol/day. Plasma TC and LDL-C were not significantly affected by these three diets despite manipulations of the key dietary fatty acids. The high 18:1 Canola and high 16:0 palm olein resulted in almost identical plasma and lipoprotein cholesterol levels.  Only HDL-C after the AHA diet was significantly raised compared to the other two diets. The findings of the above study have now become the subject of a patent [14] advocating a balanced fatty acid ratio incorporating palm oil, for maintaining an improved LDL/HDL-cholesterol ratio that could be cardio-protective. The patent findings have been commercialized as a range of TFA-free healthful margarine and solid fats and serve as a primary example how the food industry can provide functionality and health in a TFA-free environment.

References:

  1. Institute of Medicine (IOM). Letter report on dietary reference intakes for trans fatty acids. In: Dietary reference intakes for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein and amino acids. Institute of Medicine/Food and Nutrition Board. Washington, DC: National Academy Press, 2002. Internet:http://www.iom.edu/fnb (accessed 10 Oct 2002).
  2. Mensink RP, Katan MB. Effect of dietary trans fatty acids on high-density and low-density lipoprotein cholesterol levels in healthy subjects. N Engl J Med 1990; 323: 439-445.
  3. Sundram K, Anisah I, Hayes KC, Jeyamalar R, Pathmanathan R. Trans (elaidic) fatty acids adversely impact lipoprotein profiles relative to specific saturated fatty acids in humans. J Nutr 1997; 127: 514S-520S.
  4. Willett WC, Stampfer MJ, Manson JE, Colditz GA, Speizer FE, Rosner BA, Sampson LA, Hennekens CH. Intake of trans fatty acids and risk of coronary heart disease among women. Lancet 1993; 341: 581-585.
  5. Ascherio A, Hennekens CH, Buring JE, Master C, Stampfer MJ, Willett WC. Trans fatty acid intake and risk of myocardial infarction. Circulation 1994; 89: 94-101.
  6. Hu FB, St ampfer MJ, Manson JE, Rimm E, Colditz GA, Rosner BA, Hennekens CH, Willett WC. Dietary fat intake and risk of coronary heart disease in women. N Engl J Med 1997; 337: 1491-1499.
  7. Salmeron J, Hu FB, Manson JE, Stampfer MJ, Colditz GA, Rimm EB, Willett WC. Dietary fat intake and risk of type 2 diabetes in women.  Am J Clin Nutr 2001; 73:1019-26.
  8. Hunter JE. Studies on effects of dietary fatty acids as related to their position on triglycerides. Lipids 2001; 36: 655-668.
  9. Kubow S. The influence of positional distribution of fatty acids in native, interesterified and structure-specific lipids on lipoprotein metabolism and atherogenesis. J Nutr Biochem 1996; 7: 530-541.
  10. Hayes KC. Synthetic and modified glycerides: effects on plasma lipids. Curr Opin Lipidol 2001; 12: 55-60.
  11. Nor Aini I, Suria MSA. Food uses of palm and palm kernel oils. In (ed. Basiron Y, Jalani BS, Chan KW). Advances In Oil Palm Research Malaysian Palm Oil Board, Kuala Lumpur, Malaysia. p 968-1035. 2000.
  12. Sambanthamurthi R, Sundram K, Tan YA. Chemistry and biochemistry of palm oil. Progress in Lipid Research 2000; 507-558.
  13. Sundram K, Hayes KC, Siru OH. Both dietary 18:2 and 16:0 may be required to improve the serum LDL/HDL cholesterol ratio in normocholesterolemic men.  J Nutr Biochem 1995; 4: 179-187.
Sundram, K., Perlman D, Hayes, KC. Increasing the HDL level and HDL/LDL ratio in humans with fat blends. United States of American Patent No. 557 8334, 1996.


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